Diindolylmethane (DIM) A phytonutrient and plant indole is a natural compound derived from the digestion of indole-3-carbinol (I3C), which is found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage, and kale with potential antiandrogenic and antineoplastic activities. [1]
When these vegetables are chewed and digested, an enzyme called myrosinase is released, converting glucobrassicin, a compound found in these vegetables, into I3C.
I3C is converted into DIM in the acidic environment of the stomach. This conversion is significant because DIM has been shown to have various potential health benefits.
Diindolylmethane is present in Miduty's Estrogen Balance supplement within the range of 200 mg per serving (2 capsules).
Miduty Estrogen Balance supplement has 30 servings per container and the recommended consumption goes up to 2 capsules per day.
- Miduty's DIM offers a natural solution for balancing estrogen and progesterone levels, addressing a wide range of hormonal issues from menstrual irregularities to menopausal symptoms.
- Miduty's DIM helps to mitigate the effects of estrogen dominance, reducing symptoms such as hormonal acne, weight gain, and mood swings.
- Using Miduty's DIM reduces reliance on synthetic hormones and medications, which can have long-term side effects and increase the risk of serious health conditions like cancer and stroke.
- Miduty's DIM helps reduce hormonal acne and improve overall skin health, leading to a clearer complexion.
- Women experiencing menopause can benefit from Miduty's DIM, which helps manage symptoms such as hot flashes, night sweats, and mood swings.
- By balancing both male and female hormones, Miduty's DIM supports reproductive health for both sexes, improving fertility and reducing symptoms associated with hormonal imbalances.
| Uses & Benefits |
Description |
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Hormone Balance |
DIM (Diindolylmethane) plays a crucial role in promoting a healthy balance of estrogen metabolites, favoring the production of 2-hydroxy estrogen, a "good" estrogen metabolite. This balance helps reduce the risk of estrogen-dominant conditions such as breast and uterine cancers in women [2], as well as gynecomastia, or "man boobs," in men, which occurs due to high levels of estrogen. By lowering levels of 16-alpha-hydroxy estrogen, a "bad" estrogen linked to an increased risk of cancer, DIM also supports a healthy testosterone-to-estrogen ratio. For men, this is particularly important, as it helps reduce the conversion of testosterone to estrogen, managing symptoms of hormonal imbalances such as the development of breast tissue (gynecomastia), excess facial hair, and a pear-shaped body—common signs of estrogen dominance. In both men and women, DIM's ability to balance hormones can significantly improve overall health, reducing the risks associated with excess estrogen. |
|
Immune System Support |
The immune system is essential for protecting the body against infections, diseases, and foreign invaders. DIM has been shown to enhance immune function by modulating the activity of immune cells. DIM can increase the activity of various immune cells, such as T cells and natural killer (NK) cells, which play a critical role in identifying and destroying infected or cancerous cells. [3] DIM can help the body more effectively fight off viral and bacterial infections. DIM's anti-inflammatory properties help reduce chronic inflammation, thereby supporting immune health. |
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Antioxidant and Anti-inflammatory Effect |
DIM exhibits antioxidant properties, helping to neutralize free radicals and reduce oxidative stress, which can contribute to chronic diseases and aging. DIM has anti-inflammatory properties, which can help reduce inflammation-related conditions and improve overall health. [4] |
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Cancer Prevention |
DIM has been shown to inhibit the growth of breast cancer cells by promoting the production of beneficial estrogen metabolites and reducing harmful ones. In men, DIM can help prevent the development and progression of prostate cancer by modulating estrogen and testosterone metabolism. [5] DIM promotes apoptosis (programmed cell death) in cancerous cells, helping to prevent the proliferation of cancer cells. |
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Weight Management and Fat Metabolism |
DIM can aid in breaking down stored fat and support healthy weight management by enhancing fat metabolism. By balancing estrogen levels, DIM helps prevent weight gain associated with high estrogen levels, particularly in the abdominal area. |
|
Menopausal Symptoms Relief |
One of the most common symptoms of menopause is hot flashes. DIM helps to balance estrogen levels, which can reduce the frequency and severity of hot flashes. DIM can help stabilize mood swings, depression, and anxiety due to hormonal changes arising during the menopause stage. During menopause, reduced estrogen levels can lead to bone loss and an increased risk of osteoporosis. DIM can help protect against bone density loss and support overall bone health. [6] |
|
Skin Health |
Acne is often linked to hormonal fluctuations, particularly the imbalance between estrogen and androgens (male hormones present in both men and women). High androgen levels can increase sebum production, leading to clogged pores and acne. [7] By modulating the levels of androgens, DIM can help reduce sebum production and prevent the clogging of pores. This is particularly useful for individuals who suffer from acne due to high androgen levels and promotes clearer skin. |
The appropriate dosage of DIM varies depending on the purpose of use and individual factors. Commonly recommended dosages are:
With Meals: It is generally recommended to take DIM with meals. Taking DIM with food can help reduce the risk of gastrointestinal upset and improve its absorption.
Consistency: Take DIM at the same time each day to maintain consistent levels in your bloodstream.
Morning Dose: Take 100-200 mg of DIM with breakfast, including healthy fats such as avocado, nuts, or olive oil.
Evening Dose (if needed): Take an additional dose with dinner if a higher total daily dose is required or to maintain consistent levels.
DIM is generally considered safe for most people when taken at recommended dosages. However, some individuals may experience side effects, including:
Digestive Issues: Such as nausea, gas, and diarrhea.
Headaches: Some users report mild headaches.
Hormonal Effects: Although DIM helps balance hormones, excessive intake may disrupt hormonal balance.
Urine Colour: Urine's color changes can be noticed due to its natural sulphur compounds.
Fat-Soluble: DIM is fat-soluble, meaning it is better absorbed with a meal containing fat. This can enhance its bioavailability and effectiveness.
Cycling: Some individuals may benefit from cycling DIM, meaning they take it for a certain period (e.g., three months) and then take a break before resuming. This can help prevent potential tolerance or side effects.
Diindolylmethane (DIM) is a natural compound derived from the digestion of indole-3-carbinol found in cruciferous vegetables. It is known for its potential health benefits, including hormone balance, immune system support, antioxidant and anti-inflammatory effects, cancer prevention, weight management, and relief from menopausal symptoms.
DIM helps maintain a healthy balance of estrogen metabolites, which can reduce the risk of hormone-related conditions and support overall health. It also supports skin health by reducing hormonal acne and balancing androgen levels.
For optimal benefits, DIM should be taken with meals to enhance absorption and minimize gastrointestinal upset. Typical dosages range from 100-200 mg per day, but individuals with specific health concerns should consult a healthcare professional for personalized recommendations.
While generally safe, potential side effects include digestive issues, headaches, and changes in urine color. Taking DIM with fat-containing meals and possibly cycling its use can improve its effectiveness and reduce the risk of side effects.
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