Calcium-D-Glucarate (CDG) is a compound formed when calcium binds with glucaric acid, a substance produced by the body and also found in various plant sources. It's a compound naturally found in fruits and vegetables like oranges, apples, grapefruits, cabbage, broccoli, and brussels sprouts. [1]
CDG supports detoxification pathways in the liver and plays a role in the elimination of harmful substances, including toxins and excess hormones, particularly estrogen. [2]
Calcium-D-Glucarate works by inhibiting the enzyme beta-glucuronidase. This enzyme is produced by bacteria in the gut and can break the bond between toxins and glucuronic acid (a detoxifying agent), allowing the reabsorption of the toxins into the body. [3] By inhibiting beta-glucuronidase, Calcium-D-Glucarate helps prevent reabsorption of these toxins and promotes their excretion.
Calcium-D-Glucarate is present in Miduty Estrogen Balance Supplement within the range of 500 mg per serving.
Miduty Estrogen supplement has 30 servings per container with the health expert recommending consumption of 2 capsules per day — one after breakfast and one after lunch.
This compound is integral for women facing issues such as cystic acne, PMS, and fibroids, as it aids in the effective elimination of excess estrogen from the body. This detoxifying action is particularly beneficial for women dealing with conditions like PCOS, endometriosis, and perimenopause symptoms.
By reducing the levels of harmful estrogen, Calcium-D-Glucarate helps restore the delicate balance between estrogen and progesterone, alleviating symptoms such as painful periods, heavy bleeding, and mood swings.
Moreover, its inclusion enhances the overall efficacy of the supplement, supporting not just hormonal balance but also providing protective benefits against breast cancer.
With the highest strength available on the market, Calcium-D-Glucarate in Miduty’s Estrogen Balance ensures that women receive the most effective support for their hormonal health and detoxification needs.
| Benefits |
Description |
|
Hormonal Balance |
Calcium-D-Glucarate is known for its ability to help regulate estrogen levels in the body. It inhibits an enzyme called beta-glucuronidase, which can cause estrogen to be reabsorbed into the bloodstream rather than excreted. [4] This is especially beneficial for those dealing with estrogen dominance, which can lead to issues like PMS, weight gain, and hormonal imbalances. |
| Detoxification |
It plays a vital role in the liver’s detoxification process, helping the body excrete toxins more effectively. It binds to waste products in the liver, making them water-soluble, so they can be excreted through urine or bile. [5] This is particularly useful for detoxifying environmental toxins, pollutants, and carcinogens. |
| Weight Loss |
By balancing estrogen levels and promoting the removal of toxins, Calcium-D-Glucarate can aid in weight loss efforts. Excess estrogen can cause fat storage, particularly in areas like the hips and thighs, so reducing estrogen levels may lead to more effective fat metabolism. [6] |
| Cholesterol Management |
Calcium-D-Glucarate has been shown to help lower LDL cholesterol levels. [7] By supporting liver function and detoxification, it aids in the regulation of cholesterol production and helps the body eliminate excess cholesterol more effectively. |
| Improved Skin Health |
Estrogen dominance and toxin buildup can negatively affect skin health, leading to issues like acne, premature aging, and inflammation. Calcium-D-Glucarate’s detoxifying properties help cleanse the body, reducing the appearance of skin issues linked to hormonal imbalances. |
| Cancer Prevention |
Studies have suggested that Calcium-D-Glucarate may have a protective effect against certain types of cancers, particularly hormone-dependent cancers like breast, prostate, and colon cancers. [8] Its ability to lower estrogen levels and aid in detoxification may help reduce the risk of developing these cancers. |
The adequate dosage of Calcium-D-Glucarate can vary depending on age, health status, and specific needs.
General Adult Dosage: 200 mg to 1000 mg per day for overall health, detoxification, or hormonal support. Split into 2-3 doses throughout the day for better absorption.
Pregnancy and Breastfeeding: Due to the potential effects on hormone levels, it’s not recommended for pregnant or breastfeeding women.
Older Adults: Start with 200 mg to 500 mg per day, adjust based on individual needs. Consult a healthcare expert, especially if on medications or hormone therapies.
Specific Health Conditions:
For General Health and Detoxification: Calcium-D-Glucarate can be taken with or without food. However, taking it with meals may improve tolerance for some people. To enhance absorption, it’s often recommended to divide the total daily dosage into 2-3 smaller doses.
For Hormonal Imbalances (e.g., Estrogen Dominance): Taking Calcium-D-Glucarate with meals is suggested as it may support hormonal detoxification more effectively.
For Liver Detox: The body’s natural detoxification processes are often more active during the morning. Taking Calcium-D-Glucarate with breakfast can enhance liver detox support.
For Weight Loss Support: Taking it before meals may help optimize metabolism and aid in detoxifying fat-storing hormones like estrogen.
Interactions: If taking medications or other supplements, take Calcium-D-Glucarate separately, at least 2 hours apart, to avoid interactions, especially with hormone medications or supplements.
Mild Digestive Issues: Nausea, bloating, or diarrhea may occur, especially when taking large doses. It’s usually mild and can be reduced by lowering the dose or taking it with food.
Lowered Estrogen Levels: Calcium-D-Glucarate helps remove excess estrogen from the body. For individuals with already low estrogen levels, it may further reduce estrogen, potentially leading to symptoms like mood swings, fatigue, or changes in menstrual cycles.
Dehydration: Due to its detoxifying effects, some people may experience dehydration. Drinking plenty of water can help counter this effect.
Fatigue or Weakness: In rare cases, detoxification effects may cause temporary fatigue, especially when starting on higher doses.
Combine with a Healthy Diet: Calcium-D-Glucarate works best when combined with a diet rich in fruits and vegetables. Cruciferous vegetables (e.g., broccoli, and cauliflower) can enhance its detoxifying effects by providing additional glucaric acid.
Calcium D Glucarate is a valuable compound that offers numerous health benefits, including supporting detoxification, balancing hormones, and aiding weight loss.
By inhibiting harmful enzymes, it enhances the body's ability to eliminate toxins and manage estrogen levels effectively. While generally safe, it’s important to be aware of potential side effects, such as digestive issues and changes in hormone levels.
For those considering this supplement, understanding the appropriate dosage is crucial for achieving desired results while minimizing risks.
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| 4. | Gut microbial beta-glucuronidase: a vital regulator in female estrogen metabolism - PMC |
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